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A high white blood cell count usually means one of the following has increased the making of white blood cells: A high white blood cell count is an increase in cells in the blood that fight infections What's considered high in a white blood cell count varies from one lab to another A high white blood cell count plus results from other tests might show the cause of your illness Or you might need other tests for more information about your condition. Many factors can cause too few or too many white blood cells Find out more about these conditions in children. A brief increase in certain white blood cells, called lymphocytes, is typical after an infection Too high a count can mean something more serious. Learn about this cancer that forms in white blood cells called lymphocytes Treatments include chemotherapy, targeted therapy and immunotherapy. The bone marrow produces immature cells that develop into leukemic white blood cells called lymphoblasts These abnormal cells are unable to function properly, and they can. A white blood cell count that's higher than usual most commonly is due to an infection or inflammation Or it could point to an immune system disorder or a bone marrow.