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Capillary leak syndrome happens when fluid leaks from your small blood vessels into surrounding tissues It requires immediate treatment to prevent a drop in blood pressure and other serious complications Capillary leak syndrome can’t be cured, but you can reduce episodes by taking medications as prescribed. Capillary leak syndrome, or vascular leak syndrome, is characterized by the escape of blood plasma through capillary walls, from the blood circulatory system to surrounding tissues, muscle compartments, organs or body cavities It is a phenomenon most commonly witnessed in sepsis, and less frequently in autoimmune diseases, differentiation syndrome, engraftment syndrome, hemophagocytic. Capillary leak syndrome is a rare disorder that causes a dramatic drop in blood pressure Early diagnosis is important to ensure proper treatment and better outcomes. Introduction idiopathic systemic capillary leak syndrome (iscls) is a rare disorder characterized by episodes of severe hypotension, hypoalbuminemia, and hemoconcentration [1,2] During attacks of iscls, profound derangements of the vascular endothelium develop, resulting in leakage of plasma and proteins into the interstitial compartment [1,2]. Disease information summary systemic capillary leak syndrome (scls) causes fluid and proteins to leak out of tiny blood vessels (capillaries) into surrounding tissues This may lead to very low blood pressure (hypotension), hypoalbuminemia, and thickened blood due to a decrease in plasma volume (hemoconcentration). What is systemic capillary leak syndrome Systemic capillary leak syndrome (scls), also known as clarkson disease, is a rare disorder in which considerable amounts of plasma and proteins leak from capillaries into surrounding tissue, muscle, and body cavities. What is capillary leak syndrome Capillary leak syndrome is a disorder that results in the abnormal permeability of capillaries, leading to the escape of plasma and other fluids into the interstitial spaces This leakage can cause significant swelling (edema) and a decrease in blood volume, which may result in hypotension (low blood pressure) and shock Cls can occur as an isolated event or as.